When Subaru Natsuki leaves the convenience store, the last thing he expects is to be wrenched from his everyday life and dropped into a fantasy world. Things aren't looking good for the bewildered teenager; however, not long after his arrival, he is attacked by some thugs. Armed with only a bag of groceries and a now useless cell phone, he is quickly beaten to a pulp. Fortunately, a mysterious beauty named Satella, in hot pursuit after the one who stole her insignia, happens upon Subaru and saves him. In order to thank the honest and kindhearted girl, Subaru offers to help in her search, and later that night, he even finds the whereabouts of that which she seeks. But unbeknownst to them, a much darker force stalks the pair from the shadows, and just minutes after locating the insignia, Subaru and Satella are brutally murdered. However, Subaru immediately reawakens to a familiar scene—confronted by the same group of thugs, meeting Satella all over again—the enigma deepens as history inexplicably repeats itself. [Written by MAL Rewrite]

Dr. Kenzou Tenma, an elite neurosurgeon recently engaged to his hospital director's daughter, is well on his way to ascending the hospital hierarchy. That is until one night, a seemingly small event changes Dr. Tenma's life forever. While preparing to perform surgery on someone, he gets a call from the hospital director telling him to switch patients and instead perform life-saving brain surgery on a famous performer. His fellow doctors, fiancée, and the hospital director applaud his accomplishment; but because of the switch, a poor immigrant worker is dead, causing Dr. Tenma to have a crisis of conscience. So when a similar situation arises, Dr. Tenma stands his ground and chooses to perform surgery on the young boy Johan Liebert instead of the town's mayor. Unfortunately, this choice leads to serious ramifications for Dr. Tenma—losing his social standing being one of them. However, with the mysterious death of the director and two other doctors, Dr. Tenma's position is restored. With no evidence to convict him, he is released and goes on to attain the position of hospital director. Nine years later when Dr. Tenma saves the life of a criminal, his past comes back to haunt him—once again, he comes face to face with the monster he operated on. He must now embark on a quest of pursuit to make amends for the havoc spread by the one he saved. [Written by MAL Rewrite]

Fifteen-year-old Megumi Shimizu dreamed of a glamorous life in the big city; however, her unexpected death in the quiet village of Sotoba marks the beginning of what appears to be a ferocious epidemic that turns the hot summer into a season of blood and terror. A young doctor named Toshio Ozaki begins to doubt the nature of the disease and comes to understand that to discover the truth, he must abandon his humanity. Meanwhile, Natsuno Yuuki, an antisocial youth from the city, is haunted by the sudden death of Megumi and must realize the pain of friendship in the face of his own tragedy. Toshio and Natsuno form an unlikely pair as they work together to save Sotoba before it transforms into a ghost town of vampires. Shiki, adapted from the horror novel written by Fuyumi Ono, goes beyond the average vampire story. It tells the tragic tale of survival in a world where one cannot easily distinguish between good and evil. Abandoned by God, the Shiki, as the vampires call themselves, have only their will to live as they clash with the fear of the paranoid/unbelieving villagers. Shiki explores the boundary that separates man from monster. [Written by MAL Rewrite]